Lab Members


Prof. Samir Mitragotri

Professor Samir Mitragotri

Principal Investigator
Hiller Professor of Bioengineering and Hansjorg Wyss Professor of Biologically Inspired Engineering
Core Faculty Member, Wyss Institute for Biologically Inspired Engineering
Prof. Mitragotri has made groundbreaking contributions to the field of biological barriers and drug delivery. His research has advanced fundamental understanding of biological barriers and has led to the development of new materials as well as technologies for diagnosis and treatment of various ailments including diabetes, cancer, cardiovascular diseases, skin conditions and infections, among others. Many of his technologies have advanced to human clinical studies and products. At the same time, fundamental understanding developed through his research has advanced the understanding of the biology of barriers in the human body.
211 Pierce Hall

Post Docs

Pavimol Angsantikul (Keep), PhD

Pavimol Angsantikul (Keep), PhD

Postdoctoral Fellow
Oral drug delivery is considered a desirable administration route and offers multiple advantages for patients. However, the natural barriers present in the gastrointestinal tract (GI) prompts many challenges for an effective oral delivery. My research focuses on exploiting ionic liquids as a drug carrier for GI delivery application. Particularly, I am interested in the delivery of biological drugs and elucidating their fate in vivo.
Northwest Building, B160
52 Oxford Street
Cambridge, MA 02138

Junling Guo, PhD

Postdoctoral Fellow
The possibility to exploring the unique physicochemical and biological properties of polyphenols can serve as an important source of inspiration in the search for new and improved biomaterials. My research focuses on the engineering of cells with polyphenol-functionalized materials or biological molecules to pursue highly challenging biological goals.
Cambridge - Northwest Building, B164, 52 Oxford Street, Cambridge, MA 02138
Longwood - Wyss Institute, 203, 3 Blackfan Cir, Boston, MA 02115

Vinu Krishnan, MSE, PhD

Postdoctoral Fellow
My research focuses on developing safe and effective treatments for cancer. I am currently working towards the clinical translation of multi-drug loaded polymeric formulations for indications in dermatology and oncology. At extremely low doses, these formulations could save lives and improve the quality of life for every patient treated for cancer. I am looking to build strategic alliances with companies, and invite potential investors while identifying new unmet areas in the clinic for these drugs.
Northwest Building, B165
52 Oxford Street
Cambridge, MA 02138

Md "Nabi" Nurunnabi, PhD

Postdoctoral Fellow

Delivering therapeutics to the right cells of interest at the right time is not only necessary for higher therapeutic efficacy but also for limiting their off-target mediated toxicity. My interest lies on developing bioengineered advanced delivery approach for cell specific drug delivery for treatment of chronic diseases. My research within Mitragotri Lab is focused on oral delivery of large molecules and understanding their biological fate and therapeutic mechanism in cellular level.... Read more about Md "Nabi" Nurunnabi, PhD

Northwest Building, B158
52 Oxford Street
Cambridge, MA 02138

Qin Qi (Maggie), PhD

Postdoctoral Fellow
I am interested in studying drug delivery as a transport phenomenon. A fundamental understanding of transport processes in drug delivery will help us to design better drug carriers for a variety of applications. The unique densely-packed structure of the skin poses a formidable biological barrier for transdermal drug delivery. I am performing a mechanistic study of how macromolecules permeate through the skin with the aid of ionic liquids, which potentially changes the skin structure. My second research project is to systematically investigate how nanoparticle-hitchhiked red blood cells interact with the flow environment in microcirculation and explore the critical conditions for nanoparticles to detach and release drugs.
Northwest Building, B160
52 Oxford Street
Cambridge, MA 02138

C. Wyatt Shields IV, PhD

Postdoctoral Fellow
A major challenge in cell-based immunotherapies is controlling cell function once injected into the body. My research seeks to develop tools to manipulate the activation and suppression pathways of macrophages in vivo via field-responsive particle backpacks. 
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138
Tao Sun

Tao Sun, PhD

Postdoctoral Fellow
My primary research goal is to develop translational focused ultrasound (FUS) technologies in advancement of drug delivery and immunomodulation for treating cancer and neurological diseases. To overcome biological barriers which challenge drug delivery applications significantly, ultrasound-activated oscillating microbubbles are used to create stresses locally on nearby vasculature/tissue or induce biomechanical effects that promote drug penetration into tissue. The mechanical perturbations would further facilitate enhanced immune responses and neuronal activity interference. In Mitragotri Lab, I am mainly working on investigating (A) drug delivery via bio-synthetic systems and bio-inspired nanoparticles after FUS-induced blood-brain barrier disruption; (B) theranostic feasibility via particle hitch-hacking during FUS immunotherapy for brain cancer. I am co-advised by Prof. Nathan McDannold at Brigham and Women’s Hospital and Harvard Medical School.
Longwood – 221 Longwood Ave, EBRC 521, Boston, MA 02115
Cambridge – Northwest Building B160, 52 Oxford Street, Cambridge, MA 02138
Eden Tanner

Eden Tanner, PhD

Postdoctoral Fellow
Ionic liquids and deep eutectic solvents could be the key to unlocking selective, effective biomedicine - but understanding the fundamental microscopic interactions within the ionic solvents is essential. My research focuses on elucidating what is happening at a molecular level, working towards the development of smart solvents that are tailored for purpose.
Northwest Building, B160
52 Oxford Street
Cambridge, MA 02138
Zongmin Zhao

Zongmin Zhao, PhD

Postdoctoral Fellow
Immunomodulation represents a promising approach for treating many diseases and disorders prophylactically or therapeutically. My research focuses on using red blood cell hitchhiking, transdermal vaccination, and oral vaccination to modulate the immune responses. I am also interested in using synthetic platelet and platelet hitchhiking for metastatic cancer treatment.
Northwest Building, B164
52 Oxford Street
Cambridge, MA 02138

Fellows and Associates

Vimisha D

Vimisha Dharamdasani, MS

The objective of my research is to develop a novel ionic-liquid formulation for topical delivery of nucleic acids into the skin. The resulting platform will have broad applications to other nucleic acids for the treatment of a wide range of dermatological conditions. 
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138

Wei He, PhD

Biological drugs play an increasingly important role in disease theray, however, their effective delivery is challenging. My research interests predominantly include cytosol delivery of the biopharmaceutics with a drug-delivering-drug (DDD) platform and liposome-assisted (spatial) codelivery of the biologics and small-molecular drugs for combinatorial treatment. Additionally, I am focusing on the translation of several novel formulations and have wide contact with the industry.

Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138

Isabella Suzuki

I am a PhD student in Prof. Bentley's lab  at the University of São Paulo – Brazil. My research focuses on the treatment of psoriasis by silencing the TNF-alpha inflammation protein using siRNA-TNF-alpha bound to solid lipid nanoparticles (SLN). In Prof. Mitragotri´s lab, my research focuses treating psoriasis using siRNA-TNF-alpha bound to an ionic liquid, CAGE, and validating the system in mice models of psoriasis (Imiquimod method).

Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138

Jeymesson Vieira, PhD

Wound healing after skin damage is a complex process and although tissue repair is an evolution of the body itself to solve the wound, some of them need special care for proper healing. I am a professor of histology and embryology in Federal University of Pernambuco UFPE/Brazil and as a visitor professor at Mitragotri’s lab I have studied technologies to increase skin permeability in drug transport bringing transcutaneous skin therapy beyond the state-of-art.
Northwest Building, B164
52 Oxford Street
Cambridge, MA 02138

Graduate Students

Tyler Brown

Tyler Brown

Graduate Student
Delivering chemotherapeutics, neuroprotective agents, and other drugs to the brain has proven to be a challenging feat, primarily due to the physical yet dynamic blood brain barrier (BBB). My work focuses on developing a human brain-on-a-chip to better assess and help improve upon promising drug delivery technologies for the treatment of neurodegenerative and other brain-related diseases.
Wyss Institute
3 Blackfan Circle, 2nd Floor
Room 206-7A, Center for Life Science
Boston, MA
Apoorva Sarode

Apoorva Sarode

Graduate Student
Cardiovascular diseases and trauma are the leading causes of death in the world. My research work is focused on developing bioinspired polymeric platforms which can integrate the physical and biological parameters of natural platelets for targeted action. These platforms can be used to halt internal bleeding as well as for the detection and treatment of various cardiovascular diseases.
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138
Debra Wu

Debra Wu

Graduate Student
Liposomes for synergistic combination chemotherapy delivery
Northwest Building, B165
52 Oxford Street
Cambridge, MA 02138
Anvay Ukidve

Anvay Ukidve

Graduate Student
I work on improving the delivery of nanoparticles to the vascular endothelium of various organs via RBC- hitchhiking.
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138

Li-Wen Lily Wang

Graduate Student
I am a Ph.D. student in medical engineering at the Harvard-MIT Division of Health Sciences and Technology (HST). My current research interests include cell-based drug delivery for cancer immunotherapy and vaccine development.
Northwest Building, B163
52 Oxford Street
Cambridge, MA 02138
Kevin Peng

Kevin Peng

Graduate Student
Oral delivery of insulin for the treatment of diabetes has remained a highly desirable yet challenging goal for several decades due to poor absorption of proteins through the intestine. My research focuses on developing novel multifunctional nanoparticles encased in mucoadhesive patches for enhanced mucus penetration and intestinal absorption of biopharmaceuticals.
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138

Administrative Staff

Kelly Ibsen

Kelly Ibsen

Lab Coordinator
My research is focused on the use of ionic liquids in medical applications. For transdermal drug delivery, ILs can enhance penetration of macromolecules like insulin through the skin, alleviating the need for painful injections. ILs also exhibit antimicrobial activity, and are particularly good at disrupting biofilms created by some bacterial species.
Northwest Building, B164
52 Oxford Street
Cambridge, MA 02138

Lab Alumni

Former Grad Students Tenure Current Employment
Jagannathan Sundaram 1999-2002 Genentech
Joy Baxter  1999-2004 Consultant 
Ahmet Tezel 1999-2004 Novartis
Pankaj Karande 2000-2005 Rensselaer Polytechnic Institute
Elizabeth Chambers 2000-2006 Clorox
Tuan Dinh 2001-2006 Archimedes Inc.
Chinmay Pangarkar 2001-2006 Private Biotech Company
Julie Champion 2001-2007 Georgia Tech
Sumit Paliwal  2002-2007 Novartis 
Kathryn Whitehead 2002-2007 Carnegie Mellon University
Angela Zivkovich 2003-2005 US Peace Corps.
Sejal Hall 2003-2008 Novartis
Anubhav Arora 2004-2009 Noven
Tracy Hsu 2005-2011 Amgen
Nishit Doshi 2006-2010 Private Biotech Company
Poornima Kolhar 2006-2012 Private Biotech Company
Chris Brunquell 2007-2012 University of Conneticut
Aaron C. Anselmo 2010-2015 Massachusetts Institute of Technology
Kathryn Camacho 2010-2015 Bristol-Myers Squibb
Michael Zakrewsky 2010-2015 Gilead Sciences
Marta Broto (Visiting grad) 2015 Nanobiotechnology and Biomolecular for Diagnostics
Andres Da Silva (Visiting grad) 2015 University of Santiago de Compostela
Maria I. Ruocco 2013-2017 Rice University
Anshuman Dasgupta (Visiting grad) 2017-2018 RWTH AACHEN University
Mengwen Zhang 2013-2018 Dow Chemical
Douglas Vogus 2012-2018 Fount Bio, Inc.
Anusha Pusuluri 2013-2018 Kala Pharmaceuticals
David Smith 2013-2018  
Former Post Docs Tenure Current Employment
Zancong Shen 2000-2003 Ardea Biosciences
Elisabeth Kaltenbock 2001-2002 Ventura College
Amit Kumar Jain 2002-2005 Corium
Yogesh Katare 2005-2006 VNS Institute of Pharmacy, Bhopal, India
Eiichi Torisaka 2007-2008 Oita University
Alisar Zahr 2007-2008 Schepens Eye Research Institute, Harvard
Makoto Ogura  2007-2010 Hisamitsu 
Sumit Paliwal 2007-2010 Novartis
Monica James-Smith 2008-2010 The Lubrizol Corporation
Jin-Wook Yoo 2008-2011 Chosun University: College of Pharmacy
Linden Bolisay 2009-2010 L'Garde, Inc.
Yasunari Michinaka 2009-2010 Hisamitsu
Rikke Vicki Benjaminsen (Visiting Researcher) 2010 Technical University of Denmark
Nishit Doshi 2010-2011 Private Biotech Company
Zhimin Zhou (Visiting Scholar) 2010-2011 Chinese Academy of Medical Sciences
Paul Tumeh (NIH K08 trainee) 2012 UCLA Medical School
 Maarten Bakker  2013 Eindhoven University of Technology 
Sunali Bhatnagar 2013 Oxford University
Vivek Gupta  2013 Keck Graduate Institute 
Byeong Hee Hwang 2013 Incheon National University
Francesca Cavalieri  2013-2014  University of Rome
Tomoyuki Mitoma 2013-2014  Higuchi Inc.
Ming Chen 2011-2014  Xiamen University
Sutapa Barua 2011-2014  Missouri Univeristy of Science of Science and Technology
Sunny Kumar 2013-2014 Nitto Denko Corporation
Stefano Menegatti 2013-2015 North Carolina State University
Jianping Qi (Visiting Scholar) 2015-2016 Fudon University 
Yasunori Iwao (Visiting Scholar) 2015-2016 University of Shizuoka
Yen Wah Tong (Visiting Scholar) 2015-2016 National University of Singapore
Amrita Banerjee 2013-2017 North Dakota State University
Christian Agatemor 2017-2018 John Hopkins University
Shirin Mesbah Oskui 2018-2019  


Former Undergraduates Graduation
Nicarter Gordon  2000
Philip Le 2000
Elizabeth Mallon 2000
Marc Soares 2000
Ruben Ayala  2001
Kathy Bange  2001
May Brickey 2001
Justin Cisar 2001
Ocean Feniger 2001
Adam Hartwick 2001
Armondo Jimenez 2001
Richard Keeler  2001
Brian Kluck  2001
Eve Lee  2001
Penny Letts 2001
Veronica Mora 2001
 Tamara Murray 2001
Emile Plise 2001
Beison Ramirez  2001
Haydee Rodriguez  2001
Seth Sanford  2001
Vivian Shen 2001
Joe Tucherer 2001
Paul Andersen  2002
Nitasha Bakhru  2002
Nocol Balquidra  2002
Steve Bush    2002
Maria Casanon  2002
Maricela Casteneda 2002
Celia Chen 2002
Luis Diaz   2002
Lauren Fix  2002
 Michael Hedvat    2002
Jefferey Katrencik  2002
Drew Lassen  2002
Berlyn Mellein    2002
Ana Misic 2002
Cecelio Morello 2002
Jeff Oneil 2002
Brian Piorek  2002
Araceli Rojo 2002
Ashley Sanders  2002
Kelly Smith  2002
Courtney Still  2002
Ashwinin Ashokkumar 2003
Tiffany Coleman 2003
Kaitleen Ergun 2003
Tawni Koutchesfahani 2003
Thien Khahn Pham 2003
Amanda Walker 2003
Nicholas Williams 2003
Arthur Wojcicki 2003
Varun Bharadwaj  2004
Moon Jean Ho 2004
Vincent Kispersky 2004
Thomas Minner 2004
Heather Becker-Brungard 2005
Natalie Karr 2005
Santosh Gupta 2006
Gabriel Martinez 2006
Alejandro Sanchez 2006
Casey Schmidt  2006
Zareen Zapadia 2006
Holly Bovey  2008
Shayla Brooks  2008
Marjorie Fernandez  2008
David Gebauer   2008
Jordanne Gregorio 2008
Brittney Hellner  2008
Natalie Karr 2008
Alex Morales 2008
Lindsay Palmer 2008
Steven Pease 2008
David Wilson 2008
Ricardo Alamillo  2009
Nancy Annunziato 2009
Ari Pritchard-Bell 2009
Brian Ilker 2009
Rahul Lele 2010
Martin Bryant 2011
Michele Corrigan  2011
Michael Grambow 2011
Jessica Hoy  2011
Martin Manley 2011
Yuan Pan 2011
Daniel Schiffels 2011
Jordanne Wang 2011
Nathan Dias 2013
Vivian Le   2013
Shane Nourizadeh 2013
Austin Pearce 2013
Mayra Perez 2013
Annie Ragusa  2013
Ambarneil Roy 2013
Dana Rutherford 2013
Ami Thakar 2014
Vanessa Wagner 2014
Sanjana Apte  2015
Zoe Fuchs 2015
Jenny Lee 2015
Sateja Paradkar 2015
Ileana Garcia 2016
Juan Diego Carval   2016
Francis Cunningham 2016
Rohan Gogoi 2016
Joshua Sanchez De Oliveira 2016
Mayuri Kasaraneni 2016
Rohit Bhatt 2017
Gabrielle Jung 2017
Omar Lujano 2017