People

Pavimol Angsantikul (Keep), PhD

Pavimol Angsantikul (Keep), PhD

Postdoctoral Fellow
Oral drug delivery is considered a desirable administration route and offers multiple advantages for patients. However, the natural barriers present in the gastrointestinal tract (GI) prompts many challenges for an effective oral delivery. My research focuses on exploiting ionic liquids as a drug carrier for GI delivery application. Particularly, I am interested in the delivery of biological drugs and elucidating their fate in vivo.
Northwest Building, B160
52 Oxford Street
Cambridge, MA 02138
Tyler Brown

Tyler Brown

Graduate Student
Delivering chemotherapeutics, neuroprotective agents, and other drugs to the brain has proven to be a challenging feat, primarily due to the physical yet dynamic blood brain barrier (BBB). My work focuses on developing a human brain-on-a-chip to better assess and help improve upon promising drug delivery technologies for the treatment of neurodegenerative and other brain-related diseases.
Wyss Institute
3 Blackfan Circle, 2nd Floor
Room 206-7A, Center for Life Science
Boston, MA
Vimisha D

Vimisha Dharamdasani, MS

The objective of my research is to develop a novel ionic-liquid formulation for topical delivery of nucleic acids into the skin. The resulting platform will have broad applications to other nucleic acids for the treatment of a wide range of dermatological conditions. 
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138
Wei

Wei He, PhD

Biological drugs play an increasingly important role in disease theray, however, their effective delivery is challenging. My research interests predominantly include cytosol delivery of the biopharmaceutics with a drug-delivering-drug (DDD) platform and liposome-assisted (spatial) codelivery of the biologics and small-molecular drugs for combinatorial treatment. Additionally, I am focusing on the translation of several novel formulations and have wide contact with the industry.

Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138
Kelly Ibsen

Kelly Ibsen

Lab Coordinator
My research is focused on the use of ionic liquids in medical applications. For transdermal drug delivery, ILs can enhance penetration of macromolecules like insulin through the skin, alleviating the need for painful injections. ILs also exhibit antimicrobial activity, and are particularly good at disrupting biofilms created by some bacterial species.
Northwest Building, B164
52 Oxford Street
Cambridge, MA 02138
VK

Vinu Krishnan, MSE, PhD

Postdoctoral Fellow
My research focuses on developing safe and effective treatments for cancer. I am currently working towards the clinical translation of hyaluronic-acid based drug formulations for indications in dermatology and oncology. At extremely low doses, these formulations could save lives and improve the quality of life for every patient treated for cancer. I am looking to build strategic alliances with companies, and invite potential investors while identifying new unmet areas in the clinic for these drugs.
Northwest Building, B165
52 Oxford Street
Cambridge, MA 02138
Prof. Samir Mitragotri

Professor Samir Mitragotri

Principal Investigator
Hiller Professor of Bioengineering and Hansjorg Wyss Professor of Biologically Inspired Engineering
Core Faculty Member, Wyss Institute for Biologically Inspired Engineering
Prof. Mitragotri has made groundbreaking contributions to the field of biological barriers and drug delivery. His research has advanced fundamental understanding of biological barriers and has led to the development of new materials as well as technologies for diagnosis and treatment of various ailments including diabetes, cancer, cardiovascular diseases, skin conditions and infections, among others. Many of his technologies have advanced to human clinical studies and products. At the same time, fundamental understanding developed through his research has advanced the understanding of the biology of barriers in the human body.
211 Pierce Hall
Nurunnabi, Md

Md "Nabi" Nurunnabi, PhD

Postdoctoral Fellow

Delivering therapeutics to the right cells of interest at the right time is not only necessary for higher therapeutic efficacy but also for limiting their off-target mediated toxicity. My interest lies on developing bioengineered advanced delivery approach for cell specific drug delivery for treatment of chronic diseases. My research within Mitragotri Lab is focused on oral delivery of large molecules and understanding their biological fate and therapeutic mechanism in cellular level.... Read more about Md "Nabi" Nurunnabi, PhD

Northwest Building, B158
52 Oxford Street
Cambridge, MA 02138
Kevin Peng

Kevin Peng

Graduate Student
Oral delivery of insulin for the treatment of diabetes has remained a highly desirable yet challenging goal for several decades due to poor absorption of proteins through the intestine. My research focuses on developing novel multifunctional nanoparticles encased in mucoadhesive patches for enhanced mucus penetration and intestinal absorption of biopharmaceuticals.
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138
Maggie

Qin Qi (Maggie), PhD

Postdoctoral Fellow
I am interested in studying drug delivery as a transport phenomenon. A fundamental understanding of transport processes in drug delivery will help us to design better drug carriers for a variety of applications. The unique densely-packed structure of the skin poses a formidable biological barrier for transdermal drug delivery. I am performing a mechanistic study of how macromolecules permeate through the skin with the aid of ionic liquids, which potentially changes the skin structure. My second research project is to systematically investigate how nanoparticle-hitchhiked red blood cells interact with the flow environment in microcirculation and explore the critical conditions for nanoparticles to detach and release drugs.
Northwest Building, B160
52 Oxford Street
Cambridge, MA 02138
Apoorva Sarode

Apoorva Sarode

Graduate Student
Cardiovascular diseases and trauma are the leading causes of death in the world. My research work is focused on developing bioinspired polymeric platforms which can integrate the physical and biological parameters of natural platelets for targeted action. These platforms can be used to halt internal bleeding as well as for the detection and treatment of various cardiovascular diseases.
Northwest Building, B153
52 Oxford Street
Cambridge, MA 02138